html
Understanding New COVID Variant Symptoms: FLiRT Variants and the Current Landscape
Estimated reading time: 8 minutes
- FLiRT variants, while prevalent in mid-2024, have been superseded by newer strains.
- Symptoms of FLiRT variants were largely consistent with previous COVID-19 strains.
- FLiRT variants showed enhanced transmissibility and immune evasion.
- Vaccination and antiviral treatments remained effective against FLiRT variants.
- Staying up-to-date on vaccinations and following CDC guidelines remain crucial.
Table of Contents
- New COVID Variant Symptoms: FLiRT Variants
- Transmissibility and Immune Evasion of FLiRT Variants
- Severity and Public Health Guidance Regarding FLiRT Variants
- Treatment and Vaccination Strategies Against FLiRT Variants
- The Current COVID-19 Landscape (September 2025)
- Practical Takeaways and Actionable Advice
New COVID Variant Symptoms: FLiRT Variants
The FLiRT variants, named for specific mutations on their spike proteins, are descendants of the JN.1 variant prevalent during the winter of 2023-2024. While they caused a significant surge in cases, their symptoms were largely consistent with previous COVID-19 strains. There was no evidence suggesting they caused a higher rate of severe illness than their predecessors.
- Fatigue: A persistent feeling of tiredness and lack of energy.
- Fever or Chills: Elevated body temperature, often accompanied by shivering.
- Body Aches or Muscle Aches: Pain and discomfort in muscles and joints.
- Congestion or Runny Nose: Nasal congestion and/or a runny nose.
- Cough: A persistent cough, which could be dry or productive (producing mucus).
- Sore Throat: Pain or irritation in the throat.
- Headache: Pain or discomfort in the head.
- Loss of Taste and/or Smell: While less frequent than with earlier variants, some individuals experienced this symptom.
- Gastrointestinal Symptoms: Nausea, vomiting, or diarrhea were also reported.
- Shortness of Breath or Difficulty Breathing: This symptom, while less common, could indicate a more serious infection and warrants immediate medical attention.
The severity of symptoms varied significantly depending on individual factors, including pre-existing health conditions, age, vaccination status, and prior COVID-19 infections. Individuals with compromised immune systems or older adults remained at higher risk for developing severe illness, even with the FLiRT variants.
Transmissibility and Immune Evasion of FLiRT Variants
One of the defining characteristics of the FLiRT variants, particularly KP.2 and LB.1, was their enhanced transmissibility and ability to evade immunity gained from previous infections or vaccinations compared to the JN.1 variant. These mutations likely contributed significantly to their rapid spread and prevalence. This highlights the ongoing challenge of COVID-19, where viral evolution necessitates continuous adaptation of preventative and treatment strategies.
Severity and Public Health Guidance Regarding FLiRT Variants
Despite their increased transmissibility, the FLiRT variants did not generally result in more severe illness than previous strains. This is largely attributed to the increased population immunity built up through widespread vaccination efforts and previous infections. However, it is crucial to remember that vulnerable populations, such as the immunocompromised and the elderly, remained at a higher risk of severe outcomes.
- Isolation: Individuals should isolate themselves until their symptoms improve and they have been fever-free for at least 24 hours without medication.
- Precautions: After isolation, precautions such as wearing masks in public spaces and improving indoor air circulation were recommended for an additional five days.
Treatment and Vaccination Strategies Against FLiRT Variants
Fortunately, antiviral treatments like Paxlovid continued to be effective against the FLiRT variants. These treatments target parts of the virus outside the spike protein, making them less susceptible to the mutations that drive variant emergence.
Vaccination remained a cornerstone of COVID-19 prevention. Updated COVID-19 vaccines were developed to target strains like KP.2, a prominent FLiRT variant. These updated vaccines were designed to provide broader protection against circulating strains. The CDC strongly recommended that all eligible individuals remain up-to-date with their vaccinations, particularly emphasizing the importance for older adults and immunocompromised individuals.
The Current COVID-19 Landscape (September 2025)
As of September 2025, the FLiRT variants are no longer the dominant strains in the United States. They have been largely replaced by newer Omicron subvariants. XFG now accounts for approximately 78% of cases, followed by NB.1.8.1 at 14%, and LP.8.1 at 3%. Other circulating variants include XEC, XDV.1, and LF.7. The CDC continues its diligent monitoring of COVID-19 activity using various metrics, including test positivity rates and emergency department visits for respiratory illnesses.
Practical Takeaways and Actionable Advice
- Stay up-to-date on vaccinations: Receiving updated COVID-19 vaccines remains the most effective way to protect yourself against severe illness.
- Practice good hygiene: Continue to practice frequent handwashing and respiratory etiquette (covering coughs and sneezes).
- Monitor symptoms: Pay attention to your body and seek medical attention if you experience concerning symptoms.
- Follow CDC guidelines: Stay informed about the latest CDC guidance on COVID-19 prevention and treatment.
The information provided in this article is for informational purposes only and should not be considered medical advice. Always consult with a healthcare professional for any health concerns or before making any decisions related to your health or treatment.
Call to Action: For more detailed information on COVID-19 prevention, treatment, and the latest variant updates, contact us today for a consultation. Our team of experts can provide tailored advice and guidance to help you navigate the evolving pandemic landscape.